Shashank Shekhar

Publications

Research Publications

(In preparation)

  1. Shekhar S, Charles Tracy, Gouxue Wang, Juhász, Gábor, Krämer H. UFMylated ER Proteins scaffold p62 Condensates for Regulation of Neuronal Structural Plasticity. (In preparation).

(Peer reviewed):

Google scholar citation: https://scholar.google.com/citations?user=K1bphEoAAAAJ&hl=en

  1. Shekhar S, Charles Tracy, Peter V. Lidsky, Raul Andino, Katherine J Wert, and Helmut Krämer. Sensory quiescence induces a cell-non-autonomous integrated stress response curbed by condensate formation of the ATF4 and XRP1 effectors. Nature Commun. 2025,16, 252.
  2. Shekhar S#, Moehlman AT, Park B, Ewnetu M, Tracy C, Titos I, Pawłowski K, Tagliabracci VS, Krämer H#. Allnighter pseudokinase-mediated feedback links proteostasis and sleep in Drosophila. Nature Commun. 2023, 14, 2932.  [ #corresponding author]
  3. Shekhar S, M Tripathi, Aparajit B. Dey and Sharmistha Dey. Exploring the Serum Level of RE1 Silencing Transcription Factor in Alzheimer’s Disease. Ann Natl Acad Med Sci (India) 2021; 00:15.
  4. Shekhar S & Dey S. Induction of p73, Δ133p53, Δ160p53, pAKT lead to neuroprotection via DNA repair by 5-LOX inhibition. Molecular Biology Reports. 2020: 47: 269–274.
  5. Shekhar S, Yadav Y, Singh AP, Pradhan R, Desai GR, Dey AB, Dey S. Neuroprotection by ethanolic extract of Syzygium aromaticum in Alzheimer’s disease like pathology via maintaining oxidative balance through SIRT1 pathway. Exp Gerontol. 2018: 27: 110:277-283.
  6. Shekhar S, Yadav S K, Rai N, Kumar R, Yadav Y, Tripathi Manjari, Dey Aparajit B, Dey Sharmistha. 5-LOX in Alzheimer’s Disease: Potential Serum Marker and In Vitro Evidences for Rescue of Neurotoxicity by Its Inhibitor YWCS. Mol Neurobiol. 2018:55(4):2754-2762. doi: 10.1007/s12035-017-0527-1. Epub 2017 Apr 27.
  7. Shekhar S, Kumar R, Nitish Rai, Kumar V, Singh K, Upadhyay A D, Tripathi M, Dwivedi S N, Dey A B and Dey S. Estimation of Tau and Phosphorylated Tau 181 in serum of Alzheimer’s disease and Mild cognitive impairment patients. PLoS ONE. 2016 Jul 26;11(7):e0159099.
  8. Pradhan R, Yadav S K, Prem NN, Bhagel V, Pathak M, Shekhar S, Gaikwad S, Dwivedi SN, Bal C S, Dey AB, Dey S. Serum FOXO3A: A ray of hope for early diagnosis of Alzheimer’s disease. Mechanisms of Ageing and Development. 2020:190:111290.
  9. Kumar R, Singh A K, Kumar M, Shekhar S, Rai N, Kaur P, Parshad R and  Dey S. Serum 5-LOX: A progressive protein marker for breast cancer and new approach for therapeutic target. Carcinogenesis. 2016:37(9):912–917.
  10. Pradhan R, Kumar R, Shekhar S, Rai N, Ambashtha A,  Banerjee J, Pathak M, Dwivedi S N, Dey S, Dey A B. Longevity and healthy ageing genes FOXO3A and SIRT3: Serum protein marker and new road map to burst oxidative stress by Withania somnifera. Exp Gerontol. 2017:95:9-15.
  11. Singh K, Shekhar S, Yadav Y, Xess I, Dey S. DS6: anticandidal, antibiofilm peptide against Candida tropicalis and exhibit synergy with commercial drug. J Pept Sci. 2017 :23(3):228-235.
  12. Singh K, Kumar S, Shekhar S, Dhawan B, Dey S. Synthesis and biological evaluation of novel peptide BF2 as an antibacterial agent against clinical isolates of vancomycin-resistant enterococci. J Med Chem. 2014:21:8880-5.
  13. Rai N, Kumar R, Desai G R, Venugopalan G, Shekhar S, Chatterjee P, Tripathi M, Upadhyay A D, Dwivedi S N, Dey A B and Dey S. Relative alterations in Blood-Based Levels of sestrin in Alzheimer’s Disease and Mild Cognitive Impairment Patients. Journal of Alzheimer’s disease. 2016:54(3):1147-1155.
  14. Sahu V, Nigam L, Agnihotri V, Gupta A, Shekhar S, Subbarao N, Bhaskar S, Dey S. Diagnostic Significance of p38 Isoforms (p38α, p38β, p38γ, p38δ) in Head and Neck Squamous Cell Carcinoma: Comparative Serum Level Evaluation and Design of Novel Peptide Inhibitor Targeting the Same. Cancer Res Treat. 2019:51(1): 313–325.
  15. Singh A P, Nigam L, Yadav Y, Shekhar S, Subbarao N, Dey S. Design and in vitro analysis of SIRT2 inhibitor targeting Parkinson’s disease. Mol Divers (2020). https://doi.org/10.1007/s11030-020-10116-z.
  16.  Anwar M, Mallick SR, Paliwal D, Sekhar S, Panda S K, Dey S, Dey A B. Impact of physical activity on mitochondrial enzymes, muscle stem cell and antioxidant protein Sestrins in Sarcopenic mice. Exp Gerontol. 2021:15;150:111358.
  17. Kumari, S, Singh A, Singh AK, Yadav Y, Bajpai S, Upadhyay AK, Shekhar S, Dwivedi S, Dey AB, Dey S. ‘Circulatory GSK-3β: Blood-Based Biomarker and Therapeutic Target for Alzheimer’s Disease’. Journal of Alzheimer’s disease. 2022:85(1):249-260.

Publication in Book chapter

  1. Dey S, Rai N, Shekhar S, Singh A.P, Agnihotri V. (2019) Molecular Marker and Therapeutic Regimen for Neurodegenerative Diseases. In: Rath P. (eds) Models, Molecules and Mechanisms in Biogerontology. Springer, Singapore.
  2. Nandi N, Shekhar S. (2023) Role of Medical Biotechnology Research in the Field of Neurodegenerative Disease Treatment. In: Pratik Talukder (eds) Exploring Medical Biotechnology- in vivo, in vitro, in silico: Biotechnology from Labs to Clinics and Basic to Advanced. Routledge, Taylor & Francis Group.