Proteome and metabolome reprogramming in brain
My focus is to understand proteome and metabolome reprogramming by biomolecular condensate and their implications in brain ageing and neurodegeneration.
Shashank Shekhar, PhD
I am postdoc with Prof. Helmut Krämer at UT Southwestern
Medical Center. I use Drosophila to understand neuronal plasticity and proteome reprograming during stress responses.
During my PhD with Prof. Sharmistha Dey at AIIMS, New Delhi, I identified several blood-based biomarker candidates for Alzheimer’s disease and synthesized several peptides targeting neuroinflammation.
During my master’s thesis at IGIB with Dr. Hasi Rani Das, I evaluated therapeutic potential of an anti-TNFa peptide for Rheumatoid arthritis in CIA Rat model.
I am a curious neuroscientist, and my career goals are to conduct transformative research that has potential to make major impacts on neuroscience and train the next generation of scientists.
Acute stress and neuronal plasticity
Sensory disability as cell non autonomous chronic stress
